Book direct
and save up to 10%
compared to Booking.com
Check rooms and rates
From251US$ /night
Check-in
18Jan2026Select date
Check-out
19Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

167 West Main Street, Lexington, Kentucky, United States, 40507
-
Steps from Rupp Arena
Great
8.2
8.7
/10
4.5
4.2
/5

21C Museum Hotel Lexington - Contemporary art hotel near Blue Grass Airport

Occupying the historic Fayette National Bank Building, 21C Museum Hotel Lexington features over 7,000 square feet of exhibition space with rotating contemporary art installations. The property includes Lockbox restaurant, which sources ingredients from Kentucky's limestone-rich soil, and a bar with craft cocktails. Guests have access to a 24-hour business center, valet parking, and pet-friendly rooms. The hotel is 15 km from Blue Grass Airport and within walking distance of Rupp Arena and Transylvania University.

Additional perks of the hotel

Free guided art tours and cultural programming

Seasonal packages including bourbon and horse farm experiences

Private event spaces for 10-250 guests with catering by Lockbox

Complimentary Wi-Fi and PATH water bottles as part of sustainability efforts

Rooms overview

Guest rooms feature custom-designed furnishings, Malin + Goetz bath amenities, and original artwork. Options include City Queen rooms with one queen bed, Deluxe King rooms with king-sized beds, and Corner King rooms with two exposures. The Skylight Suite includes a skylight and separate living area, while the Two-bedroom Suite has two en-suite bathrooms and downtown views. All rooms have 42-inch HDTVs and blackout drapery.

Other conveniences

Free Wi-Fi and alarm clock/docking stations

Plush robes and heated bathroom tiles in select suites

Connecting rooms available between Deluxe Suites and Deluxe Kings

Cribs available at no charge, rollaway beds for $30 nightly

Must-do experiences

  • Explore the Lexington Farmers Market for fresh local produce.
  • Visit the Mary Todd Lincoln House for a glimpse of history.
  • Savor a Hot Brown sandwich at the historic Brown Hotel.
  • Tour the Lexington Cemetery for its beautiful sculptures and stories.
  • Discover local art at the LexArts Gallery on Main Street.
View all

Choose Your Room

Our listed hotels offer a variety of room types—double rooms, family suites, or deluxe options—all with features like breakfast, flexible cancellation policies, and exclusive deals.
City Queen Room
2 persons
240 sq. feet 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
360 sq. feet 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
335 sq. feet 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
435 sq. feet 
1 King-size bed
Shower
Coffee machine
Click button to see more rooms
Show all rooms
Show all roomsLess

Room Rates & Availability Tracker

Find Deals for Your Travel Dates

Amenities

Thoughtful hotel amenities for a comfortable stay

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
Show more

Dining Onsite

At 21C Museum Hotel Lexington, guests can delight in a tapestry of authentic American flavors and local culinary treasures. Each dining option is thoughtfully crafted to offer menus accommodating various dietary preferences in a warm and inviting atmosphere.
21C Museum Hotel Lexington Restaurant photo

Lockbox

American, Local
Ambiance
Stylish and contemporary with an intimate vibe, Lockbox welcomes guests into a warm space adorned with art, creating a unique dining experience.
Key Offerings
Lockbox features a diverse menu that celebrates local ingredients, with options for breakfast and dinner, including vegetarian, vegan, gluten-free, and dairy-free selections.
Reservation
Recommended
Wednesday to Friday: 7 AM - 11 AM & 5 PM - 10 PM; Saturday: 7 AM - 11 AM & 5 PM - 11 PM; Sunday: 10 AM - 2 PM & 5 PM - 9 PM.

Red River Rockhouse

Café with a focus on sustainability
Ambiance
A charming, family-owned café, Red River Rockhouse bursts with eclectic decor and a cozy atmosphere perfect for casual dining.
Key Offerings
Dedicated to sourcing ingredients locally, guests enjoy wholesome meals with an emphasis on sustainability and standout options like delectable burritos and refreshing margaritas.
Reservation
Not needed
Hours vary.

La Cabana Mexican Restaurant

Mexican
Ambiance
A lively and vibrant setting serving up authentic Mexican fare that evokes the spirit of Mexico in every bite.
Key Offerings
Guests delight in well-earned burritos and house-special margaritas, ideal for a casual but satisfying meal.
Reservation
Not needed
Hours vary.

Miguel's Pizza

Pizza
Ambiance
An informal eatery known for its rustic charm and lively atmosphere, Miguel's Pizza is a local staple perfect for a quick and satisfying bite.
Key Offerings
Indulge in slices of 'za from this infamous spot, paired perfectly with a laid-back vibe after a day of exploration.
Reservation
Not needed
Hours vary.

Hotel Location

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
1600 ft
Museum
Hunt-Morgan House
1600 ft
Event hall
Lexington Convention Center
1500 ft
Theatre
Kentucky Theatre
1200 ft
440 W Short St
Explorium
1500 ft
University
University of Kentucky
300 ft
Park
Triangle Park
1200 ft
Church
St Paul the Apostle Catholic Church
1500 ft
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
900 ft
Shopping Area
Victorian Square Shoppes
1200 ft
Square
Phoenix Park
600 ft
Gallery
Limestone Blue
500 ft
Lexington Financial Center
Isaac Murphy Memorial Art Garden
500 ft
Gallery
Pam Miller Downtown Arts Center
800 ft
Gallery
ArtsPlace
800 ft
7285 Huron Street
Huron Street Gallery
900 ft
Gratz Park
1700 ft
Restaurants
Bourbon on Rye
300 ft
115 W Main St
Corto Lima
600 ft
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
400 ft
163 West Short Street
Bluegrass Tavern
500 ft
115 Cheapside
Horse And Jockey
700 ft
131 Cheapside
Buddha Lounge
700 ft
109 N Mill St
Explore Lexington
Explore Lexington
Top Attractions
Activities
Dining
Entertainment
Rupp Arena
Rupp Arena
6-minute walk
Home to University of Kentucky's basketball games, Rupp Arena hosts concerts and events, attracting sports and music fans alike.
Mary Todd Lincoln House
Mary Todd Lincoln House
9-minute walk
This historic home offers a glimpse into the life of Mary Todd Lincoln. Guided tours provide rich insights into its history.
University of Kentucky Art Museum
University of Kentucky Art Museum
13-minute walk
Featuring a diverse collection, this museum showcases American art alongside contemporary and historical pieces. Special events often hosted.
Lexington Convention Center
Lexington Convention Center
6-minute walk
This central venue hosts exhibitions, conventions, and cultural events, making it a bustling hub in downtown Lexington.
Horse Country Tours
12-minute walk
Guided tours through beautiful horse farms showcase Lexington's equestrian heritage. Advanced booking is recommended during peak seasons.
Yoga in the Park
25-minute walk
Relaxing yoga sessions hosted at local parks provide a serene environment. Classes are open to all skill levels, with mats available.
Bourbon on Rye
Bourbon on Rye
1-minute walk
Cozy and stylish, this restaurant serves bourbon-infused dishes. Signature item: The Bourbon Burger. Reservations recommended on weekends.
Corto Lima
Corto Lima
3-minute walk
This vibrant spot offers a modern take on Latin cuisine. Notable for its small plates and fresh cocktails. Vegetarian options available.
School Sushi
School Sushi
2-minute walk
A casual sushi bar renowned for its creative rolls and affordable prices. Ideal for quick bites or relaxed dining with friends.
Kentucky Theatre
Kentucky Theatre
5-minute walk
This historic venue screens independent and classic films, hosting various events like film festivals. Perfect for cultural enthusiasts.
Manchester Music Hall
Manchester Music Hall
15-minute walk
Vibrant music venue featuring live performances across genres. Offers an energetic atmosphere suitable for all ages.
Transportation Tips
City Centre
Lexington5 min  ·  1400 ft
Airports
Blue Grass Airport (LEX)21 min  ·  8.5 mi
Unlock Early Booking Discounts
Grab Your Special Rates Today!
Check Rates
Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in public areas for free.
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
15
Number of rooms:
85
Questions of the users
About 21C Museum Hotel Lexington
Are dogs welcome at the hotel?
07 November 2024
Yes! Pets are allowed in the hotel.
Is there complimentary parking available or is parking paid?
15 December 2024
Valet parking is $30 per night with unlimited in-and-out access. There are public parking options nearby if you prefer not to valet.
What are the pet policies, including fees?
22 October 2024
A one-time fee of $50 is charged for pets, and there is no limit on the number of pets allowed in the room.
Do any of the rooms feature bathtubs?
12 January 2025
Rooms with oversized bathtubs include the Deluxe Suites and the 21c Suite.
Are there spa services available on the premises?
15 February 2025
Unfortunately, there are no spa services available onsite, but arrangements for offsite spa services and in-room massages can be made.
What are the parking options for valeting a car?
03 March 2025
The hotel offers valet parking at $30 per night, allowing guests to access their vehicle as needed. The valet service operates 24/7.
Are there options for connecting rooms for families or groups?
29 April 2025
Yes, there are several connecting room options available, allowing for flexible arrangements for families or groups traveling together.
How secure is the area surrounding the hotel?
18 May 2025
The neighborhood is considered very safe, with 24-hour staffing, overnight security, and a police station located only two blocks away.
Can I arrange for an early check-in if needed?
27 June 2024
Guests can check in early at no additional charge as soon as the room is ready. To guarantee early arrival before 4 pm, it may be necessary to book the night prior.
What is the Wi-Fi situation in guest rooms?
10 September 2024
Complimentary high-speed Wi-Fi is available for all guests throughout the hotel.

Next best alternative

Consider them for your next trip.
Check-in
18Jan2026Select date
Check-out
19Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Need more options?
Check Top hotels near 21C Museum Hotel Lexington
Residence Inn By Marriott Lexington City Center Exterior photo
Mobile-only price

Residence Inn By Marriott Lexington City Center

8.3
Great106 reviews
70m from property
USD 199USD 179
per night
Lexington Marriott City Center Exterior photo
Mobile-only price

Lexington Marriott City Center

7.7
Very good99 reviews
111m from property
USD 324USD 291
per night
Hilton Lexington Downtown Hotel Interior photo
Mobile-only price

Hilton Lexington Downtown Hotel

8.1
Great640 reviews
272m from property
USD 92USD 82
per night